Unlocking new avenues to accelerate Alzheimer’s drug discovery
Accelerating drug discovery in neurodegenerative diseases through causal analysis of ageing processes in simple organisms
Although there has been great progress in basic and preclinical research for neurodegenerative disease, we have yet to identify the key underlying molecular defects or pathways that give rise to many of these conditions — observations which would yield precise targets for novel drugs.
- FDA July 2021
Through causal inference modelling of simple organisms, we have found a new way forward.
This is based on the equivalence of the biological processes (not animal models) between ageing and disease progression.
Simple Organism Systems
Shared biological processes
Unlocked cellular dynamics